bosentan Things To Know Before You Buy
six The phosphodiesterase-5 inhibitor sildenafil is certified for PAH in FC I–IV inside the USA and FC II–III in Europe. Endothelin receptor antagonists (ERAs) including bosentan, sitaxentan and ambrisentan are oral therapies licensed to be used in PAH. As no oral agent has revealed superiority there stays debate regarding which needs to be use